Opportunistic Invasion of the Heart in Hispanic Patients with Acquired Immunodeficiency Syndrome

Pablo I. Altieri Department of Medicine and Pathology, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico

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Consuelo Climent Department of Medicine and Pathology, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico

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German Lazala Department of Medicine and Pathology, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico

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Roman Velez Department of Medicine and Pathology, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico

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Jose V. Torres Department of Medicine and Pathology, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico

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One hundred consecutive patients who died of the acquired immunodeficiency syndrome (AIDS) were studied with an emphasis on the heart. Thirty-two patients showed pathologic changes. The pathologic findings included infection by Histoplasma capsulatum, Toxoplasma gondii, Mycobacterium tuberculosis, cytomegalovirus, Cryptococcus neoformans, and atypical mycobacteria. Noninfectious pathologic findings included nonspecific myocarditis, focal necrosis, focal fibrosis, and acute subendocardial infarction.

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