Thrombocytopenic Purpura due to Fuadin (Stibophen)

Julio V. Rivera The San Patricio Veterans Administration Hospital, Bayamón District Hospital, and the School of Medicine, University of Puerto Rico, San Juan

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Hector F. Rodriguez The San Patricio Veterans Administration Hospital, Bayamón District Hospital, and the School of Medicine, University of Puerto Rico, San Juan

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E. Pérez-Santiago The San Patricio Veterans Administration Hospital, Bayamón District Hospital, and the School of Medicine, University of Puerto Rico, San Juan

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DOI:
https://doi.org/10.4269/ajtmh.1956.5.863
Volume/Issue:
Volume 5: Issue 5
Page(s):
863–868
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Summary

A case of immune thrombocytopenic purpura due to Fuadin has been reported. The reaction occurred on 2 occasions when the drug was given. Administration of plasma from this patient to a recipient who also received Fuadin produced thrombocytopenia without purpura. It is postulated that thrombocytopenic purpura in this patient was due to the occurrence of a drug-antibody complex capable of destroying or agglutinating platelets and depressing megakaryocyte activity.

Author Notes

Published Online:
Sep 1956
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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