Final Report on the First use of Puromycin for the Treatment of Sleeping Sickness

Carlos Trincão Department of Hematology and Protozoology of the Institute of Tropical Medicine, and the Missão de Estudo e Combate à Doença do Sono na Guiné Portuguesa

Search for other papers by Carlos Trincão in
Current site
Google Scholar
PubMed
Close
,
A. R. Pinto Department of Hematology and Protozoology of the Institute of Tropical Medicine, and the Missão de Estudo e Combate à Doença do Sono na Guiné Portuguesa

Search for other papers by A. R. Pinto in
Current site
Google Scholar
PubMed
Close
,
Almeida Franco Department of Hematology and Protozoology of the Institute of Tropical Medicine, and the Missão de Estudo e Combate à Doença do Sono na Guiné Portuguesa

Search for other papers by Almeida Franco in
Current site
Google Scholar
PubMed
Close
, and
Alfredo Nogueira Department of Hematology and Protozoology of the Institute of Tropical Medicine, and the Missão de Estudo e Combate à Doença do Sono na Guiné Portuguesa

Search for other papers by Alfredo Nogueira in
Current site
Google Scholar
PubMed
Close
Restricted access

Summary

Of 15 cases of sleeping sickness treated with Puromycin, 5 relapsed and 10 were free of infection, clinically and parasitologically, 25 months after treatment. No other specific drug was administered at any time to any of the 10 patients who did not relapee.

Author Notes

Save