Unusual Neurologic Manifestations Occurring during Dengue Fever Infection

O. Patey Department of Infectious and Tropical Diseases, and Laboratory of Microbiology, Villeneuve St. Georges Hospital, Villeneuve St. Georges, France

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L. Ollivaud Department of Infectious and Tropical Diseases, and Laboratory of Microbiology, Villeneuve St. Georges Hospital, Villeneuve St. Georges, France

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J. Breuil Department of Infectious and Tropical Diseases, and Laboratory of Microbiology, Villeneuve St. Georges Hospital, Villeneuve St. Georges, France

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C. Lafaix Department of Infectious and Tropical Diseases, and Laboratory of Microbiology, Villeneuve St. Georges Hospital, Villeneuve St. Georges, France

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DOI:
https://doi.org/10.4269/ajtmh.1993.48.793
Volume/Issue:
Volume 48: Issue 6
Page(s):
793–802
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This is a report on dengue fever in two young patients in France that were infected in New Caledonia and Thailand. Both presented with unusual neurologic manifestations. The first patient developed a focal subarachnoid hemorrhage that was associated with transient thrombocytopenia. No neurologic vascular malformation was detected; a mild dengue hemorrhagic fever after a previous dengue infection was suspected. The second patient showed peripheral facial palsy one week after apyrexia without any other etiology except the dengue infection. This case was probably a postinfectious syndrome associated with dengue virus. Both patients recovered spontaneously. The circumstances of the neurologic manifestations in these patients may be attributed to the dengue fever virus. However, although neurologic complciations reported for dengue fever are unusual, it is reasonable to consider these manifestations as being due to immunopathologic consequences.

Author Notes

Copyright:
Copyright © 1993 by The American Society of Tropical Medicine and Hygiene 1993
Published Online:
Jun 1993
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637

Diagnostic Procedures and Reagents

Technics for the Laboratory Diagnosis and Control of the Communicable Diseases, American Public Health Association, Ed., pp. v plus 589, 6 plates in color, cloth, New York, Am. Pub. Health Assoc. Inc., 1950, $6.00

An Introduction to Medical Protozoology

With Chapters on the Spirochaetes and on Laboratory Methods. By Robert Knowles, B.A., M.R.C.S., L.R.C.P., Lt. Col., Indian Medical Service, Calcutta. Thacker, Spink and Company. 1928. Pages I–XII, 1–887

Author:
Chas. F. Craig
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