Zygomycosis Mimicking Paranasal Malignancy

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  • Departments of Internal Medicine, Radiology, and Pathology, Medical College of Ohio, Toledo, Ohio
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A case of zygomycosis involving the maxillary sinus in a normal host and mimicking paranasal malignancy is presented. Computed tomographic images showing destruction of adjoining bony structures and histologic features of fungi are described and presented. A successful outcome was achieved with amphotericin B irrigation and parenteral amphotericin B. Nasal biopsy should be advised by both radiologists and clinicians in all cases of lesions that look like malignancy in the sinus areas before a treatment modality is initiated.