Naturally Acquired Circumsporozoite Antibodies and their Role in Protection in Endemic Falciparum and Vivax Malaria

Chansuda Wongsrichanalai United States Army Medical Component, Armed Forces Research Institute of Medical Sciences; Malaria Division, Ministry of Public Health, Bangkok, Thailand

Search for other papers by Chansuda Wongsrichanalai in
Current site
Google Scholar
PubMed Close
,
H. Kyle Webster United States Army Medical Component, Armed Forces Research Institute of Medical Sciences; Malaria Division, Ministry of Public Health, Bangkok, Thailand

Search for other papers by H. Kyle Webster in
Current site
Google Scholar
PubMed Close
,
Barnyen Permpanich United States Army Medical Component, Armed Forces Research Institute of Medical Sciences; Malaria Division, Ministry of Public Health, Bangkok, Thailand

Search for other papers by Barnyen Permpanich in
Current site
Google Scholar
PubMed Close
,
Nipon Chuanak United States Army Medical Component, Armed Forces Research Institute of Medical Sciences; Malaria Division, Ministry of Public Health, Bangkok, Thailand

Search for other papers by Nipon Chuanak in
Current site
Google Scholar
PubMed Close
, and
Sanchai Ketrangsri United States Army Medical Component, Armed Forces Research Institute of Medical Sciences; Malaria Division, Ministry of Public Health, Bangkok, Thailand

Search for other papers by Sanchai Ketrangsri in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.1991.44.201
Volume/Issue:
Volume 44: Issue 2
Page(s):
201–204
Restricted access
Get Permissions

The role of naturally acquired circumsporozoite (CS) antibodies in protection against falciparum and vivax malaria was evaluated in a group of Thai endemic villagers using a prospective cohort and a case-control study design. There was no evidence of protection by either the presence of positive CS antibody levels at the presumed time of sporozoite exposure or in individuals who persistently had measurable levels of the antibodies. The study defined levels of CS antibodies that were not protective in natural infection.
Copyright:
Copyright © 1991 by The American Society of Tropical Medicine and Hygiene 1991
Published Online:
Feb 1991
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Past two years Past Year Past 30 Days
Abstract Views 281 77 3
Full Text Views 11 0 0
PDF Downloads 8 0 0
 
Membership Banner
 
 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save