Author:
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1581 | 1172 | 62 |
| Full Text Views | 38 | 8 | 0 |
| PDF Downloads | 56 | 15 | 0 |
Ultrasonographical Investigation of Periportal Fibrosis in Children with Schistosoma mansoni Infection: Evaluation of Morbidity
Ekkehard Doehring-Schwerdtfeger
Ekkehard Doehring-Schwerdtfeger
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Ekkehard Doehring-Schwerdtfeger in
Current site
Google Scholar
PubMed
Search for other papers by Ekkehard Doehring-Schwerdtfeger in
Current site
Google Scholar
PubMed
Ibrahim M. Abdel-Rahim
Ibrahim M. Abdel-Rahim
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Ibrahim M. Abdel-Rahim in
Current site
Google Scholar
PubMed
Search for other papers by Ibrahim M. Abdel-Rahim in
Current site
Google Scholar
PubMed
Qurashi Mohamed-Ali
Qurashi Mohamed-Ali
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Qurashi Mohamed-Ali in
Current site
Google Scholar
PubMed
Search for other papers by Qurashi Mohamed-Ali in
Current site
Google Scholar
PubMed
Mamoun Elsheikh
Mamoun Elsheikh
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Mamoun Elsheikh in
Current site
Google Scholar
PubMed
Search for other papers by Mamoun Elsheikh in
Current site
Google Scholar
PubMed
Jens Schlake
Jens Schlake
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Jens Schlake in
Current site
Google Scholar
PubMed
Search for other papers by Jens Schlake in
Current site
Google Scholar
PubMed
Rüdiger Kardorff
Rüdiger Kardorff
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Rüdiger Kardorff in
Current site
Google Scholar
PubMed
Search for other papers by Rüdiger Kardorff in
Current site
Google Scholar
PubMed
Doris Franke
Doris Franke
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Doris Franke in
Current site
Google Scholar
PubMed
Search for other papers by Doris Franke in
Current site
Google Scholar
PubMed
Christoph Kaiser
Christoph Kaiser
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Christoph Kaiser in
Current site
Google Scholar
PubMed
Search for other papers by Christoph Kaiser in
Current site
Google Scholar
PubMed
Jochen H. H. Ehrich
Jochen H. H. Ehrich
Kinderklinik, Medizinische Hochschule Hannover, Division of Tropical Pediatrics, Childrens' Hospital, University of Heidelberg, Faculty of Medicine, University of Gezira, Federal Republic of Germany
Search for other papers by Jochen H. H. Ehrich in
Current site
Google Scholar
PubMed
Search for other papers by Jochen H. H. Ehrich in
Current site
Google Scholar
PubMed
Morbidity of Schistosoma mansoni infection was assessed in 536 infected Sudanese schoolchildren using an ultrasonographical staging system for periportal fibrosis of the liver. S. mansoni ova excretion in stools was mild in 28%, moderate in 58%, and severe in 14% of the patients. Grade 1 periportal fibrosis was found in 10.3%, grade 2 in 23.1%, and grade 3 in 4.7% of S. mansoni-infected children. Girls and boys were equally affected. The distribution of periportal fibrosis compared to the age of patients was homogeneous. There was no significant difference of the rate of periportal fibrosis in the 3 groups of intensity of infection. However, in the 204 patients who showed periportal fibrosis, there was a strong relation between severity of ultrasonographically detectable fibrosis with intensity of egg excretion. In 332 children, of which 73 had a heavy infection, no signs of periportal fibrosis were detected. Sudanese children show a variable susceptibility towards the development of S. mansoni-induced periportal fibrosis. High risk patients can be detected at a childhood stage by measuring the intensity of infection and investigating the liver by ultrasound.
Author Notes
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 1581 | 1172 | 62 |
| Full Text Views | 38 | 8 | 0 |
| PDF Downloads | 56 | 15 | 0 |