Detection of Specific Anti-Giardia Serum Antibody by an Immunofluorescence Test in Children with Clinical Giardiasis

Lázara Rojas Instituto de Medicina Tropical “Pedro Kouri” (IPK), Ciudad de la Habana, Cuba

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Dinorah R. Torres Instituto de Medicina Tropical “Pedro Kouri” (IPK), Ciudad de la Habana, Cuba

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Barbara J. Mediola Instituto de Medicina Tropical “Pedro Kouri” (IPK), Ciudad de la Habana, Cuba

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Carlos M. Finlay Instituto de Medicina Tropical “Pedro Kouri” (IPK), Ciudad de la Habana, Cuba

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DOI:
https://doi.org/10.4269/ajtmh.1989.40.477
Volume/Issue:
Volume 40: Issue 5
Page(s):
477–479
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In 50 of 100 children with clinical giardiasis studied, the presence of Giardia lamblia was proven by stool and/or duodenal aspirate examination; the presence of the parasite was not demonstrated in the rest. Serum antibodies to G. lamblia were investigated in all children by an indirect immunofluorescent test (IIF) with G. lamblia trophozoites as antigen. It was found that all the children with positive duodenal aspirate had positive serology (titers ≥ 1/32). The best correlation between parasitological and serological procedures were in the 1–5-year-old age group, and there was an age dependent increase of the antibody titer. Most of the parasitologically negative children were serologically negative. Our results support the use of IIF as a useful diagnostic procedure in the diagnosis of giardiasis in children.
Copyright:
Copyright © 1989 by The American Society of Tropical Medicine and Hygiene 1989
Published Online:
May 1989
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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