Experimental Transmission of Crimean-Congo Hemorrhagic Fever Virus by Hyalomma Truncatum Koch

Thomas M. Logan Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland

Search for other papers by Thomas M. Logan in
Current site
Google Scholar
PubMed
Close
,
Kenneth J. Linthicum Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland

Search for other papers by Kenneth J. Linthicum in
Current site
Google Scholar
PubMed
Close
,
Charles L. Bailey Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland

Search for other papers by Charles L. Bailey in
Current site
Google Scholar
PubMed
Close
,
Douglas M. Watts Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland

Search for other papers by Douglas M. Watts in
Current site
Google Scholar
PubMed
Close
, and
James R. Moulton Disease Assessment Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland

Search for other papers by James R. Moulton in
Current site
Google Scholar
PubMed
Close
Restricted access

Larval Hyalomma truncatum ticks were infected with Crimean-Congo hemorrhagic fever (CCHF) virus by allowing them to engorge on viremic newborn mice. The overall tick infection rate was 4.4% (24/542). Virus was detected in specimens for ≥160 days postinfection. Transstadial transmission to the adult tick stage was observed and horizontal transmission to a mammalian host was demonstrated. Horizontal transmission of CCHF virus to uninfected adult ticks occurred while feeding with transstadially infected ticks on the same host. No evidence of transovarial virus transmission from infected female ticks to their 1st generation progeny was observed.

Save