Epidemiology of Hepatitis B in the Gezira Region of Sudan

Kenneth C. HyamsU.S. Naval Medical Research Unit No. 3, Omdurman Municipal Hospital, Central Public Health Laboratory, American Embassy, Cairo, Egypt

Search for other papers by Kenneth C. Hyams in
Current site
Google Scholar
PubMed
Close
,
Mohamed A. Al-ArabiU.S. Naval Medical Research Unit No. 3, Omdurman Municipal Hospital, Central Public Health Laboratory, American Embassy, Cairo, Egypt

Search for other papers by Mohamed A. Al-Arabi in
Current site
Google Scholar
PubMed
Close
,
Ahmed A. Al-TaganiU.S. Naval Medical Research Unit No. 3, Omdurman Municipal Hospital, Central Public Health Laboratory, American Embassy, Cairo, Egypt

Search for other papers by Ahmed A. Al-Tagani in
Current site
Google Scholar
PubMed
Close
,
James F. MessiterU.S. Naval Medical Research Unit No. 3, Omdurman Municipal Hospital, Central Public Health Laboratory, American Embassy, Cairo, Egypt

Search for other papers by James F. Messiter in
Current site
Google Scholar
PubMed
Close
,
Abdella A. Al-GaaliU.S. Naval Medical Research Unit No. 3, Omdurman Municipal Hospital, Central Public Health Laboratory, American Embassy, Cairo, Egypt

Search for other papers by Abdella A. Al-Gaali in
Current site
Google Scholar
PubMed
Close
, and
John F. GeorgeU.S. Naval Medical Research Unit No. 3, Omdurman Municipal Hospital, Central Public Health Laboratory, American Embassy, Cairo, Egypt

Search for other papers by John F. George in
Current site
Google Scholar
PubMed
Close
Restricted access

To determine the prevalence of and risk factors for hepatitis B infection in rural Sudan, 2 villages in the Gezira were surveyed. There were 851 subjects (age 1–89 years; mean age 24.6 years) of equal sex distribution, 408 from Khalawaat and 443 from Saleim. HBsAg was found in 18.7%, and seropositivity for any hepatitis marker (HBsAg, anti-HBs, or anti-HBc) was found in 63.9%. The prevalence of HBsAg was highest in subjects <5 years of age (32.3%). Seropositivity for any hepatitis marker increased from 48.4% in subjects <5 years to 88.5% in persons ≥50 years of age. HBeAg was present in 70% of HBsAg-positive women of childbearing age. Residence in Khalawaat and parenteral therapy for malaria were found to be independent risk factors for HBsAg-positivity. Age, residence in Khalawaat, crowding, and having had a tattoo were predictive of seropositivity for any hepatitis marker. The reason for increased markers of hepatitis B in Khalawaat compared to Saleim was not apparent.

Save