Prepared under the auspices of The American Society of Clinical Pathologists. By John A. Kolmer, M.D., Dr.P.H., D.Sc., LL.D., and Fred Boerner, V.M.D. Assisted by C. Z. Garber, A.B., M.D., and Committees of The American Society of Clinical Pathologists. Pp. I–XXII. 1–663. D. Appleton and Company, New York and London, 1931
Ninety-five Honduran laborers with multiple intestinal worm infections were treated with piperazine citrate liquid or capsules. Eighty (94 per cent) of 85 men with Ascaris lumbricoides infections were cured, many of them on only 2.0 grams in a single daily dose for 3 days. The drug seemed to have little effect against Trichuris trichiuris in the dosages employed, and no effect against Necator americanus. No toxicity was observed.