Treatment of Multiple Intestinal Worm Infections with Piperazine Citrate

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  • Medical Service of the Tela Railroad Company (United Fruit Company) Hospital at La Limo, Honduras, C. A.


Ninety-five Honduran laborers with multiple intestinal worm infections were treated with piperazine citrate liquid or capsules. Eighty (94 per cent) of 85 men with Ascaris lumbricoides infections were cured, many of them on only 2.0 grams in a single daily dose for 3 days. The drug seemed to have little effect against Trichuris trichiuris in the dosages employed, and no effect against Necator americanus. No toxicity was observed.