edited by W. H. Taliaferro, Division of Biological and Medical Research, Argonne National Laboratory, Argonne, Illinois, and J. H. Humphrey, National Institute of Medical Research, London, England. Vol. 1, x + 423 pages, illustrated. New York, London, Academic Press. 1961. $12.00
V. Evaluation of Cross-Immunity against Type 1 Dengue Fever in Human Subjects Convalescent from Subclinical Natural Japanese Encephalitis Virus Infection and Vaccinated with 17D Strain Yellow Fever Vaccine
We examined the effect of concurrent infection with Plasmodium yoelii and Leishmania mexicana amazonensis on the course of each disease in leishmania resistant C57B1/6 mice. P. yoelii parasitemia was greatly enhanced when L. m. amazonensis was inoculated 2 days, 3 weeks, or 12 weeks prior to the malaria. Lesions due to L. m. amazonensis were enhanced in mice concomitantly infected with P. yoelii compared to mice infected with L. m. amazonensis only. Metastatic L. m. amazonensis lesions developed in mice infected with P. yoelii and L. m. amazonensis, but never in mice only infected with L. m. amazonensis.