A Human Case of Encephalitis Associated with Vesicular Stomatitis Virus (Indiana Serotype) Infection

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  • * Gorgas Memorial Laboratory, Panama City, Republic of Panama
  • | Department of Pediatrics, Hospital Del Niho, Panama City, Republic of Panama
  • | Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510
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This paper describes a case of severe encephalitis in a 3-year-old Panamanian boy infected with the Indiana serotype of vesicular stomatitis virus. The virus was recovered from the child's throat on the fifth day of illness and a rise in neutralizing antibody titer was demonstrated in paired serum specimens. This is the second report of childhood encephalitis associated with vesicular stomatitis virus infection. These suggest that infection with vesicular stomatitis viruses may cause severe disease. Human infection with vesicular stomatitis viruses is common throughout the tropical Americas.

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