by A. Trevor Willis, M.D., B.S. (Melb.), Ph.D. (Leeds), M.C.Path., M.C.P.A., Reader in Microbiology, Monash University, formerly Lecturer in Bacteriology, University of Leeds. xiv + 234 pages, illustrated, second edition. Butterworth Inc., Washington. 1965. $8.50
1 Division of Vector-Borne Viral Diseases, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, P.O. Box 2087, Fort Collins, Colorado 80522-2087
* Institute of Virology “Dr. J. M. Vanella,” Faculty of Medical Sciences, University of Cordoba, Estafeta 32, 5000 Cordoba, Argentina
Maguari virus has been classified as a subtype of Cache Valley virus. Seven Bunyamwera serogroup viruses (including prototypes Cache Valley and Maguari viruses), 4 viruses shown in previous tests as close antigenic relatives of Maguari or Cache Valley viruses, and Xingu virus were cross-tested by serum dilution-plaque reduction neutralization. All viruses were distinguishable from prototypes Cache Valley and Maguari viruses. The close antigenic relationships of the Cache Valley-like viruses demonstrate that multiple subtypes of Cache Valley virus exist and suggest that such antigenic variation is a phenotypic expression of considerable genetic diversity.