Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Past two years Past Year Past 30 Days
Abstract Views 276 92 3
Full Text Views 18 6 1
PDF Downloads 24 10 2
 
 
 
 
 
 
 
 
 
 
 

In Vitro Cultivation of Exoerythrocytic Stages of the Human Malaria Parasite Plasmodium Malariae

Pascal MilletMalaria Branch, Division of Parasitic Diseases Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333

Search for other papers by Pascal Millet in
Current site
Google Scholar
PubMedClose
,
William E. CollinsMalaria Branch, Division of Parasitic Diseases Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333

Search for other papers by William E. Collins in
Current site
Google Scholar
PubMedClose
,
Tamara L. FiskMalaria Branch, Division of Parasitic Diseases Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333

Search for other papers by Tamara L. Fisk in
Current site
Google Scholar
PubMedClose
, and
Phuc Nguyen-DinhMalaria Branch, Division of Parasitic Diseases Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Atlanta, Georgia 30333

Search for other papers by Phuc Nguyen-Dinh in
Current site
Google Scholar
PubMedClose
View More View Less
DOI:
https://doi.org/10.4269/ajtmh.1988.38.470
Volume/Issue:
Volume 38: Issue 3
Page(s):
470–473
Restricted access
Get Permissions

Exoerythrocytic stage parasites of Plasmodium malariae were obtained in vitro by inoculating primary cultures of hepatocytes from a chimpanzee (Pan troglodytes) and a monkey (Aotus lemurinus griseimembra) with sporozoites. Schizonts were observed in chimpanzee hepatocytes 8, 11, and 13 days after inoculation. Only 1 schizont was seen in Aotus hepatocytes at day 13. The morphology and development rates of P. malariae exoerythrocytic stages obtained in vitro were similar to those previously described in vivo.
Copyright:
Copyright © 1988 by The American Society of Tropical Medicine and Hygiene 1988
Accepted:
24 Sep 1987
|
Published Online:
May 1988
Save