Author:
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Warren K. S., 1979. The pathogenesis of hepatosplenic schistosomiasis: From man to monkey to mouse to molecule. Pages 439–455 inPopper H., Schaffner F., eds., Progress in Liver Disease, Volume6. Grune and Stratton, New York
-
2.
Warren K. S., DeWitt W. B., 1958. Production of portal hypertension and esophageal varices in the mouse. Proc. Soc. Exp. Biol. Med., 98 :99–101.
-
3.
Dunn M.A., Kamel R., 1981. Hepatic schistosomiasis. Hepatology, 1 :653–661.
-
4.
Andrade Z. A., Warren K. S., 1984. Mild prolonged schistosomiasis in mice: Alterations in host response with time and the development of portal fibrosis. Trans. R. Soc. Trop. Med. Hyg., 58 :53–57.
-
5.
Boros D. L., Pelley R. P., Warren K. S., 1975. Spontaneous modulation of granulomatous hypersensitivity in schistosomiasis mansoni. J. lmmunol., 114 :1437:1441.
-
6.
Colley D. G., 1976. Adoptive suppression of granuloma formation. J. Exp. Med., 143 :696–700
-
7.
Chensue S. W., Wellhausen S. R., Boros D. L., 1981. Modulation of granulomatous hypersensitivity. II. Participation of Ly-1+ and Ly-2+ T lymphocytes in the suppression of granuloma formation and lymphokine production in Schistosoma mansoni-infected mice. J. lmmunol., 127 :363–367.
-
8
Hood A. T., Boros D. L., 1980. The effect of splenectomy on the pathophysiology and eggspecific immune response of Schistosoma mansoni-infected mice, Am. J. Trop. Med. Hyg., 29 :586–591.
-
9.
Weinstock J. V., Ehrinpreis M. N., Boros D. L., Gee J. B., 1981, The effect of SQ 14225, an inhibitor of angiotensin I-converting enzyme, on the granulomatous response to Schistosoma mansoni eggs in mice. J. Clin. Invest., 67 :931–936.
-
10.
Takahashi S., Dunn M.A., Seifter S., 1980. Liver collagenase in murine schistosomiasis. Gastroenterology, 78 :1425–1431.
-
11.
Grimaud J. A., Druguet M., Peyrol S., Chevalier O., Herbage D., El Badrawy N ., 1980. Collagen immunotyping in human liver. Light and electron microscope study. J. Histochem. Cytochem., 28 :1145–1156
-
12.
Nishimura M., Asahi M., Hayashi M., Takazono I., Tanaka Y., Kohda H., Urabe H., 1985. Extracellular matrix in hepatic granulomas of mice infected with Schistosoma mansoni. Arch. Pathol. Lab. Med., 109 :813:818.
-
13.
Emonard H., Peyrol S., Guerret-Stocker S., Druguet M., Grimaud J. A., 1986. Antibody to CB-peptide a 2-CB(3,5) from type I collagen is a tissular marker of matrix degradation in hepatic murine schistosomiasis. Cell. Molec. Biol., 32 :633–640.
-
14.
Biempica L., Dunn M.A., Kamel I. A., Kamel R., Hait P. K., Fleischner C., Biempica S. L., Wu C. H., Rojkind M., 1983. Liver collagen-type characterization in human schistosomiasis. A histological, ultrastructural and immunocytochemical correlation. Am. J. Trop. Med. Hyg., 32 :316:325.
-
15.
AI Adnani M. S., 1985. Concomitant immunohistochemical localization of fibronectin and collagen in schistosome granuloma. J. Pathol., 147 :77–85.
-
16.
Andrade Z. A., Grimaud J. A., 1986. Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy. Am. J. Pathol., 124 :59–65.
-
17.
Wu C. H., Giambrone M. A., Howard D. J., Rojkind M., Wu G. Y., 1982. The nature of the collagen in hepatic fibrosis in advanced murine schistosomiasis. Hepatology, 2 :366–371
-
18.
Parise E. R., Summerfield J. A., Hahn E., Wiedmann K. H., Doenhoff M. J., 1985. Basement membrane proteins and type III procollagen in murine schistosomiasis. Trans. R. Soc. Trop. Med. Hyg., 79 :663–670.
-
19.
Weinstock J. V., Boros D. L., 1981.Heterogeneity of the granulomatous response in the liver, colon, ileum and ileal Peyer’s patches in schistosome eggs in murine schistosomiasis mansoni. J. Immunol., 127 :1906–1909.
-
20.
Weinstock J. V., Boros D. L., 1983. Organ dependent differences in composition and function observed in hepatic and intestinal granulomas isolated from mice with schistosomiasis mansoni. J. Immunol., 130 :418–422.
-
21.
Grimaud J. A., Druguet M., Peyrol S., Guerret S., 1986. Collagen. Pages 186–202 inBergmeyer H. U., ed., Methods of Enzymatic Analysis, Volume 9: Proteins and Peptides. Weinheim VCH, West Germany.
-
22.
Cameron G. R., Ganguly N. C., 1963. An experimental study of the pathogenesis and reversibility of schistosomal hepatic fibrosis J. Pathol. Bacteriol., 87 :217–237.
-
23.
Cheever A. W., Dunn M. A., Dean D. A., Duvall R. H., 1983, Differences in hepatic fibrosis in ICR, C3H and C57BL/6 mice infected with Schistosoma mansoni. Am. J. Trop. Med. Hyg., 32 :1364–1369.
-
24.
Warren K. S., 1966. The pathogenesis of “claypipe stem cirrhosis” in mice with chronic schistosomiasis mansoni, with a note on the longevity of the schistosomes. Am. J. Pathol., 49 :477–489.
-
25.
Postlethwaite A. E., Keski-Oja J., Balian G., Kang A. H., 1981. Induction of fibroblast chemotaxis by fibronectin . a 140.000 molecular weight non-gelatin binding region. J. Exp. Med., 153 :494–499.
-
26.
Bitterman P. B., Rennard S. I., Adelberg S., Crystal R. G., 1983. Role of fibronectin as a growth factor for fibroblasts. J. Cell. Biol., 97 :1925–1932.
-
27.
Ruoslahti E., Engvall E., Hayman E. G., 1981. Fibronectin: Current concepts of its structure and function. Collagen Ref. Res., 1 :95–128.
-
28.
Wyler D. J., Postlethwaite A. E., 1983. Fibroblast stimulation in schistosomiasis. IV. Isolated egg granulomas elaborate a fibroblast chemoattractant in vitro. J. lmmunol., 130 :1371–1375.
-
29.
Grimaud J. A., Borojevic R., 1977. Myofibroblasts in hepatic schistosomal fibrosis. Experientia, 33 :890–892.
-
30.
McGee J. O. D., Patrick R. S., 1972. The role of perisinusoidal cells in hepatic fibrogenesis. An electron microscopic study of acute carbon tetrachloride liver injury. Lab. Invest., 26 :429–440.
-
31.
Clement B., Grimaud J. A., Campion J. P., Deugnier Y., Guillouzo A., 1986. Cell types involved in collagen and fibronectin production in normal and fibrotic human liver. Hepatology, 6 :225–234.
-
32.
Borojevic R., Vinhas S. A., Monteiro A. N. A., Domont G. B., Zyngier F. R., Grimaud J. A., 1985. Liver connective tissue cells isolated from human schistosomal fibrosis or alcoholic cirrhosis represent a modified phenotype of smooth muscle cells. Biol. Cell, 53 :231–238.
-
33.
Olds G. R., Griffin A., Kresina T. F., 1985. Dynamics of collagen accumulation and polymorphism in murine Schistosoma japonicum. Gastroenterology, 89 :617–624.
-
34.
Andrade Z. A., Cheever A. W., 1971. Alterations of the intrahepatic vasculature in hepatosplenic schistosomiasis mansoni. Am. J. Trop. Med. Hyg., 20 :425–432.
-
35.
Takahashi S, Simpser E., 1981. Granuloma collagenase and EDT A-sensitive neutral protease production in hepatic murine schistosomiasis. Hepatology, 1 :211–220.
-
36.
Truden J. L., Boros D. L., 1985. Collagenase, elastase and nonspecific protease production by vigorous or immunomodulated liver granulomas and granuloma macrophages/eosinophils of S. mansoni infected mice. Am. J. Pathol., 121 :166–175.
-
37.
Rojkind M., Kershenobicb D., 1983. Liver fibrosis: A dynamic process? Pages 126–142 inCosmos G. C., Thaler H., eds., Clinical Hepatology. Springer-Verlag, New York.
-
38.
Piez K. A., Reddi A. H., 1984. Extracellular Matrix Biochemistry. Elsevier Science Publishing Co. Inc., New York.
-
39.
Nimni K. A., Reddi A. H., 1984. Extracellular Matrix Biochemistry. 13 :1–86.
-
40.
Seyer J. M., 1985. Mediators of increased collagen synthesis in fibrosing organs. Fund. Appl. Toxicol., 5 :228–239.
-
41.
Fleishmajer R., Gay S., Meigel W. N., Perlish J. S., 1978. Collagen in the cellular and fibrotic stages of scleroderma. Arthr. Rheum., 21 :418–428.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 371 | 125 | 7 |
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Collagen Isotypes, Laminin, and Fibronectin in Granulomas of the Liver and Intestines of Schistosoma Mansoni-Infected Mice
J. A. Grimaud
J. A. Grimaud
*CNRS UA 602, Institut Pasteur, 77 rue Pasteur, 69365 Lyon, France,
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D. L. Boros
D. L. Boros
†Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, Michigan 48201
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C. Takiya
C. Takiya
*CNRS UA 602, Institut Pasteur, 77 rue Pasteur, 69365 Lyon, France,
‡Departamento de Patologia, UFRJ, Rio de Janeiro, Brasil
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R. C. Mathew
R. C. Mathew
†Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, Michigan 48201
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H. Emonard
H. Emonard
*CNRS UA 602, Institut Pasteur, 77 rue Pasteur, 69365 Lyon, France,
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Patterns of fibrosis within hepatic and intestinal granulomas of Schistosoma mansoni-infected mice were analyzed by indirect immunofluorescence. Deposition of collagen isotypes, laminin, and fibronectin was evaluated semiquantitatively between 8 and 20 weeks of the infection. Liver granulomas were the largest at 8 weeks and contained low amounts of type I and higher amounts of type III collagen and fibronectin. Collagen deposition became pronounced as infection progressed. The relative amounts of type I collagen deposits rose and equalled that of type III. In the smaller immunomodulated granulomas at 20 weeks both types I and III were high, and type IV collagen deposition was observed. Fibronectin and laminin deposits were also detected. The small ileal granulomas did not change their size during the course of the infection. At 8 weeks, connective tissue matrix deposition was barely detectable within these lesions. Gradually, small deposits of types I and III appeared in equal amounts and attained highest levels by 20 weeks of the infection. Fibronectin deposits at that time were very prominent but laminin and type IV collagen were absent. Colon granulomas at 8 weeks of the infection were only somewhat smaller than those of the liver, yet contained very sparse deposits of types I and III collagen. During the ensuing weeks collagen deposits rose only slightly. By 20 weeks the granulomas diminished in size and within those lesions type III collagen was predominant. Whereas the presence of fibronectin was pronounced, type IV collagen and laminin were detectable only in trace amounts. These observations indicate the existence of important organ-related differences in the intragranulomatous deposition of connective tissue matrix.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
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-
1.
Warren K. S., 1979. The pathogenesis of hepatosplenic schistosomiasis: From man to monkey to mouse to molecule. Pages 439–455 inPopper H., Schaffner F., eds., Progress in Liver Disease, Volume6. Grune and Stratton, New York
-
2.
Warren K. S., DeWitt W. B., 1958. Production of portal hypertension and esophageal varices in the mouse. Proc. Soc. Exp. Biol. Med., 98 :99–101.
-
3.
Dunn M.A., Kamel R., 1981. Hepatic schistosomiasis. Hepatology, 1 :653–661.
-
4.
Andrade Z. A., Warren K. S., 1984. Mild prolonged schistosomiasis in mice: Alterations in host response with time and the development of portal fibrosis. Trans. R. Soc. Trop. Med. Hyg., 58 :53–57.
-
5.
Boros D. L., Pelley R. P., Warren K. S., 1975. Spontaneous modulation of granulomatous hypersensitivity in schistosomiasis mansoni. J. lmmunol., 114 :1437:1441.
-
6.
Colley D. G., 1976. Adoptive suppression of granuloma formation. J. Exp. Med., 143 :696–700
-
7.
Chensue S. W., Wellhausen S. R., Boros D. L., 1981. Modulation of granulomatous hypersensitivity. II. Participation of Ly-1+ and Ly-2+ T lymphocytes in the suppression of granuloma formation and lymphokine production in Schistosoma mansoni-infected mice. J. lmmunol., 127 :363–367.
-
8
Hood A. T., Boros D. L., 1980. The effect of splenectomy on the pathophysiology and eggspecific immune response of Schistosoma mansoni-infected mice, Am. J. Trop. Med. Hyg., 29 :586–591.
-
9.
Weinstock J. V., Ehrinpreis M. N., Boros D. L., Gee J. B., 1981, The effect of SQ 14225, an inhibitor of angiotensin I-converting enzyme, on the granulomatous response to Schistosoma mansoni eggs in mice. J. Clin. Invest., 67 :931–936.
-
10.
Takahashi S., Dunn M.A., Seifter S., 1980. Liver collagenase in murine schistosomiasis. Gastroenterology, 78 :1425–1431.
-
11.
Grimaud J. A., Druguet M., Peyrol S., Chevalier O., Herbage D., El Badrawy N ., 1980. Collagen immunotyping in human liver. Light and electron microscope study. J. Histochem. Cytochem., 28 :1145–1156
-
12.
Nishimura M., Asahi M., Hayashi M., Takazono I., Tanaka Y., Kohda H., Urabe H., 1985. Extracellular matrix in hepatic granulomas of mice infected with Schistosoma mansoni. Arch. Pathol. Lab. Med., 109 :813:818.
-
13.
Emonard H., Peyrol S., Guerret-Stocker S., Druguet M., Grimaud J. A., 1986. Antibody to CB-peptide a 2-CB(3,5) from type I collagen is a tissular marker of matrix degradation in hepatic murine schistosomiasis. Cell. Molec. Biol., 32 :633–640.
-
14.
Biempica L., Dunn M.A., Kamel I. A., Kamel R., Hait P. K., Fleischner C., Biempica S. L., Wu C. H., Rojkind M., 1983. Liver collagen-type characterization in human schistosomiasis. A histological, ultrastructural and immunocytochemical correlation. Am. J. Trop. Med. Hyg., 32 :316:325.
-
15.
AI Adnani M. S., 1985. Concomitant immunohistochemical localization of fibronectin and collagen in schistosome granuloma. J. Pathol., 147 :77–85.
-
16.
Andrade Z. A., Grimaud J. A., 1986. Evolution of the schistosomal hepatic lesions in mice after curative chemotherapy. Am. J. Pathol., 124 :59–65.
-
17.
Wu C. H., Giambrone M. A., Howard D. J., Rojkind M., Wu G. Y., 1982. The nature of the collagen in hepatic fibrosis in advanced murine schistosomiasis. Hepatology, 2 :366–371
-
18.
Parise E. R., Summerfield J. A., Hahn E., Wiedmann K. H., Doenhoff M. J., 1985. Basement membrane proteins and type III procollagen in murine schistosomiasis. Trans. R. Soc. Trop. Med. Hyg., 79 :663–670.
-
19.
Weinstock J. V., Boros D. L., 1981.Heterogeneity of the granulomatous response in the liver, colon, ileum and ileal Peyer’s patches in schistosome eggs in murine schistosomiasis mansoni. J. Immunol., 127 :1906–1909.
-
20.
Weinstock J. V., Boros D. L., 1983. Organ dependent differences in composition and function observed in hepatic and intestinal granulomas isolated from mice with schistosomiasis mansoni. J. Immunol., 130 :418–422.
-
21.
Grimaud J. A., Druguet M., Peyrol S., Guerret S., 1986. Collagen. Pages 186–202 inBergmeyer H. U., ed., Methods of Enzymatic Analysis, Volume 9: Proteins and Peptides. Weinheim VCH, West Germany.
-
22.
Cameron G. R., Ganguly N. C., 1963. An experimental study of the pathogenesis and reversibility of schistosomal hepatic fibrosis J. Pathol. Bacteriol., 87 :217–237.
-
23.
Cheever A. W., Dunn M. A., Dean D. A., Duvall R. H., 1983, Differences in hepatic fibrosis in ICR, C3H and C57BL/6 mice infected with Schistosoma mansoni. Am. J. Trop. Med. Hyg., 32 :1364–1369.
-
24.
Warren K. S., 1966. The pathogenesis of “claypipe stem cirrhosis” in mice with chronic schistosomiasis mansoni, with a note on the longevity of the schistosomes. Am. J. Pathol., 49 :477–489.
-
25.
Postlethwaite A. E., Keski-Oja J., Balian G., Kang A. H., 1981. Induction of fibroblast chemotaxis by fibronectin . a 140.000 molecular weight non-gelatin binding region. J. Exp. Med., 153 :494–499.
-
26.
Bitterman P. B., Rennard S. I., Adelberg S., Crystal R. G., 1983. Role of fibronectin as a growth factor for fibroblasts. J. Cell. Biol., 97 :1925–1932.
-
27.
Ruoslahti E., Engvall E., Hayman E. G., 1981. Fibronectin: Current concepts of its structure and function. Collagen Ref. Res., 1 :95–128.
-
28.
Wyler D. J., Postlethwaite A. E., 1983. Fibroblast stimulation in schistosomiasis. IV. Isolated egg granulomas elaborate a fibroblast chemoattractant in vitro. J. lmmunol., 130 :1371–1375.
-
29.
Grimaud J. A., Borojevic R., 1977. Myofibroblasts in hepatic schistosomal fibrosis. Experientia, 33 :890–892.
-
30.
McGee J. O. D., Patrick R. S., 1972. The role of perisinusoidal cells in hepatic fibrogenesis. An electron microscopic study of acute carbon tetrachloride liver injury. Lab. Invest., 26 :429–440.
-
31.
Clement B., Grimaud J. A., Campion J. P., Deugnier Y., Guillouzo A., 1986. Cell types involved in collagen and fibronectin production in normal and fibrotic human liver. Hepatology, 6 :225–234.
-
32.
Borojevic R., Vinhas S. A., Monteiro A. N. A., Domont G. B., Zyngier F. R., Grimaud J. A., 1985. Liver connective tissue cells isolated from human schistosomal fibrosis or alcoholic cirrhosis represent a modified phenotype of smooth muscle cells. Biol. Cell, 53 :231–238.
-
33.
Olds G. R., Griffin A., Kresina T. F., 1985. Dynamics of collagen accumulation and polymorphism in murine Schistosoma japonicum. Gastroenterology, 89 :617–624.
-
34.
Andrade Z. A., Cheever A. W., 1971. Alterations of the intrahepatic vasculature in hepatosplenic schistosomiasis mansoni. Am. J. Trop. Med. Hyg., 20 :425–432.
-
35.
Takahashi S, Simpser E., 1981. Granuloma collagenase and EDT A-sensitive neutral protease production in hepatic murine schistosomiasis. Hepatology, 1 :211–220.
-
36.
Truden J. L., Boros D. L., 1985. Collagenase, elastase and nonspecific protease production by vigorous or immunomodulated liver granulomas and granuloma macrophages/eosinophils of S. mansoni infected mice. Am. J. Pathol., 121 :166–175.
-
37.
Rojkind M., Kershenobicb D., 1983. Liver fibrosis: A dynamic process? Pages 126–142 inCosmos G. C., Thaler H., eds., Clinical Hepatology. Springer-Verlag, New York.
-
38.
Piez K. A., Reddi A. H., 1984. Extracellular Matrix Biochemistry. Elsevier Science Publishing Co. Inc., New York.
-
39.
Nimni K. A., Reddi A. H., 1984. Extracellular Matrix Biochemistry. 13 :1–86.
-
40.
Seyer J. M., 1985. Mediators of increased collagen synthesis in fibrosing organs. Fund. Appl. Toxicol., 5 :228–239.
-
41.
Fleishmajer R., Gay S., Meigel W. N., Perlish J. S., 1978. Collagen in the cellular and fibrotic stages of scleroderma. Arthr. Rheum., 21 :418–428.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 371 | 125 | 7 |
| Full Text Views | 10 | 2 | 2 |
| PDF Downloads | 7 | 1 | 1 |