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-
1.
Nardin E. H. , Nussenzweig V. , Nussenzweig R. S. , Collins W. E. , Harinasuta K. T. , Tapchaisri P. , Chomcharn Y. , 1982. Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and P. vivax. J. Exp. Med. 156: 20–30.
-
2.
Zavala F., Cochrane A. H., Nardin E. H., Nussenzweig R. S., Nussenzweig V., 1983. Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes. J. Exp. Med., 157: 1947–1957.
-
3.
Ballou W. R., Rothbard J., Wirtz R. A., Gordon D. M., Williams J. S., Gore R. W., Schneider I., Hollingdale M. R., Beaudoin R. L., Maloy W. L., Miller L. H., Hockmeyer W. T., 1985. Immunogenicity of synthetic peptides from circumsporozoite protein of Plasmodium falciparum. Science, 228: 996–999.
-
4.
Dame J. B., Williams J. L., McCutchan T. F., Weba J. L., Wirtz R. A., Hockmeyer W. T., Maloy W. L., Haynes J. D., Schneider I., Roberts D., Sanders G. S., Reddy E. P., Diggs C. L., Miller L. H., 1984. Structure of the gene encoding the irnmunodorninant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum. Science, 225: 593–599.
-
5.
Enea V., Ellis J., Zavala F., Arnot D. E., Asavanich A., Masuda A., Quakyi I., Nussenzweig R. S., 1984. DNA cloning of Plasmodium falciparum circumsporozoite gene: Amino acid sequence of repetitive epitope. Science, 225: 628–630.
-
6.
Zavala F., Tam P., Hollingdale M. R., Cochrane A. H., Quakyi I., Nussenzweig R. S., Nussenzweig V., 1985. Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science, 228:1436–1440.
-
7.
Campbell G. H., Brandling-Bennett A. D., Roberts J. M., Collins F. H., Barber A. M., Turner A., 1987. Detection of antibodies in human sera to the repeating epitope of the circumsporozoite protein of Plasmodium falciparum using the synthetic peptide, (NANP)3, in an enzyme-linked immunosorbent assay (ELISA). Am. J. Trop. Med. Hyg., 37: 19–23.
-
8.
Hoffman S. L., Wistar R., Ballou W. R., Hollingdale M. R., Wirtz R. A., Schneider I., Marwoto H. A., Hockmeyer W. T., 1986. Immunity to malaria and naturally acquired antibodies to the circumsporozoite protein of Plasmodium falciparum. N. Engl. J. Med., 315: 601–606.
-
9.
Druilhe P., Pradier O., Marc J-P., Miltgen F., Mazier D., Parent G., 1986. Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection. Infect. Immun., 53: 393–397.
-
10.
Nardin E. H., Nussenzweig R., McGregor I., Bryan J., 1979. Antibodies to sporozoites: Their frequent occurrence in individuals living in an area of hyperendemic malaria. Science, 206: 597-599.
-
11.
Tapchaisri P., Chomcharn Y., Poonthong C., Asavanich A., Limsuwan S., Maleevan O., Tharavanij S., Harinasuta T., 1983. Antisporozoite antibodies induced by natural infection. Am. J. Trop. Med. Hyg., 32: 1203–1208.
-
12.
Nardin E. H., Nussenzweig R. S., Bryan J. H., McGregor I. A., 1981. Congenital transfer of antibodies against malarial sporozoites detected in Gambian infants. Am. J. Trop. Med. Hyg., 30: 1159–1163.
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Age-Specific Prevalence of Antibody to a Synthetic Peptide of the Circumsporozoite Protein of Plasmodium Falciparum in Children from Three Villages in Kenya
The presence of antibody to the repeating epitope of the circumsporozoite protein of Plasmodium falciparum was determined in children 1 month to 10 years old from three villages in western Kenya using the synthetic peptide (PNAN)5 in an enzyme-linked immunosorbent assay. The percentage of antibody-positive children increased with age and differed in the three villages. The village with the lowest percentage of antibody-positive children had the lowest percentage of infections as determined by detection of blood stage parasites. The villages also differed in the age at which antibody first appeared. In one village, only 12% of the children had antibody by the age of 5; while in the other two villages, 60% and 73% had antibody by 4 years of age.