Antigenic Differences between Insect- and Culture-Derived Trypanosoma cruzi Metacyclic Trypomastigote Extracts

Salvatore Giovanni de SimoneDepartment of Immunology, WHO Collaborating Centre for Research and Training in the Immunology of Parasitic Diseases, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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Lain Carlos Pontes de CarvalhoDepartment of Immunology, WHO Collaborating Centre for Research and Training in the Immunology of Parasitic Diseases, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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Bernardo Galvão-CastroDepartment of Immunology, WHO Collaborating Centre for Research and Training in the Immunology of Parasitic Diseases, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil

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Antigenic differences between extracts prepared from insect- and axenic culture-derived T. cruzi were demonstrated by a protein A-binding immunoradiometric assay.

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