Dengue 3 Virus Transmission in Africa

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  • 1 San Juan Laboratories, Dengue Branch, Division of Vector-Borne Viral Diseases, Center for Infectious Diseases, Centers for Disease Control, U.S. Public Health Service, U.S. Department of Health and Human Services, GPO Box 4532, San Juan, Puerto Rico
  • | * Ministerio de Saude, C.P. 264, Maputo, Mozambique

The first known transmission of dengue 3 virus in Africa was documented by virus isolation during an epidemic of dengue-like illness in Pemba, Mozambique, in late 1984 and early 1985. Dengue 3 virus was the only serotype isolated. Most patients appeared to be experiencing secondary flavivirus infections, but whether this was the result of previous dengue, yellow fever, or other flavivirus infection is not known. Two cases of hemorrhagic disease with shock and death were associated with the epidemic.