Developments in Biological Standardization, Volume 59: Standardization and Control of Biologicals Produced by Recombinant DNA Technology

edited by the International Association of Biological Standardization. viii + 216 pages, illustrated. S. Karger AG, P.O. Box CH-4009, Basel, Switzerland. 1985. $30.00

James B. Kaper Center for Vaccine Development University of Maryland, Baltimore, Maryland 21201

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Volume 59 of Developments in Biological Standardization is a compilation of research papers presented at an international symposium held in Geneva in November 1983. As with other volumes in this series, the individual contributions vary greatly in length, format, quality and relevance. Contributors include people from academia, industry and governmental regulatory agencies. The overall format consists of research or short review papers followed by a page of the recorded discussion.

Session I is entitled “General Aspects” and is really a grab bag of four articles dealing with the cloning of heavily methylated DNA from fish lymphocystis disease, Escherichia coli expression vectors for regulated high level expression of eukaryotic genes, cloning of very large DNA fragments and reduction of proteolytic breakdown in microbial homogenates.

The second session is entitled “Bacteria, Parasites, Interferon” and contains two papers on bacterial disease and one each on parasites and interferon.

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