Evaluation of Febrile Patients in Port Sudan, Sudan: Isolation of Dengue Virus

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  • * U.S. Naval Medical Research Unit No. 3 (NAMRU-3), Cairo, Egypt
  • | ** Department of Veterinary Pathology, Armed Forces Institute of Pathology, Washington, DC
  • | Armed Forces Medical Corps and Ministry of Health, Democratic Republic of Sudan

One hundred consecutive patients admitted to the Port Sudan Hospital with a temperature ≥ 100°F were evaluated. Enteric fever was diagnosed in 19 patients and malaria in 13. Virologic studies identified 21 cases of dengue infection. One dengue 1 and 17 dengue 2 infections were diagnosed by viral isolation. Three untyped dengue infections were identified serologically. The clinical presentation and course of patients infected with dengue virus were most consistent with classic dengue fever. There was no evidence of hemorrhagic phenomena or shock in any of the dengue-infected patients. Both dengue 1 and 2 must be considered causes of acute fever in East Africa.