Infection of Mosquitoes with Plasmodium vivax from Chimpanzees Using Membrane Feeding

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  • 1 Malaria Branch, Division of Parasitic Diseases, Center for Infectious Diseases, Centers for Disease Control, U.S. Department of Health and Human Services, Division of Pathobiology and Immunobiology and Division of Veterinary Medicine, Atlanta, Georgia 30333
  • | * Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia 30322

Six splenectomized chimpanzees were infected with the Chesson or the North Korean strains of Plasmodium vivax. Heparinized blood taken from the animals was fed to approximately 45,000 mosquitoes using parafilm membranes. High-level mosquito infections were obtained with the blood from 4 animals. One animal infected mosquitoes only at a very low level. The other chimpanzee failed to produce a parasitemia high enough to warrant mosquito feeding.

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