Malaria and the Red Cell: Progress in Clinical and Biological Research, Volume 155

Proceedings of a malaria workshop held in conjunction with the Sixth International Conference on Red Cell Metabolism and Function, Ann Arbor, Michigan, October 2, 1983, edited by John W. Eaton and George J. Brewer. 174 pages. Alan R. Liss, Inc., 150 Fifth Avenue, New York, New York 10011. 1984. $36.00.

Susan G. Langreth Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road Bethesda, Maryland 20814-4799

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This volume consists of thirteen papers that were presented at a small workshop on malaria. Each paper is accompanied by a discussion of it by the conferees. The purpose of the workshop was to encourage a broadening of the scope of current research on malaria to include more investigation of the basic biology of the parasite/host cell interaction. It is hoped that greater understanding of the physical and biochemical inter-relationships between the malaria parasite and its host erythrocyte may eventually stimulate new immunologic or chemotherapeutic approaches to the control of malaria. The book is divided into three sections: metabolism (four papers), membranes and membrane proteins (five papers), and chemotherapy and drug resistance (four papers). All of the papers deal either with Plasmodium falciparum in vitro or with Plasmodium berghei in the mouse. Most contributions are in research paper format.

The metabolism section includes papers on glutathione metabolism, host superoxide dismutase, and calcium metabolism in malaria-infected erythrocytes as well as a provocative review ofoxidative stress and falciparum malaria.