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Chloroquine-Resistant Falciparum Malaria in Northern Malawi
Martin S. Wolfe
Martin S. Wolfe
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Joel G. Breman
Joel G. Breman
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Beatrice Ainsworth
Beatrice Ainsworth
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Awash Teklehaimanot
Awash Teklehaimanot
Office of Medical Services, Department of State, Malaria Branch, Centers for Disease Control, Washington, DC, Malawi
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Leslie C. Patchen
Leslie C. Patchen
Office of Medical Services, Department of State, Malaria Branch, Centers for Disease Control, Washington, DC, Malawi
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An American Peace Corps volunteer contracted chloroquine-resistant Plasmodium falciparum malaria while serving in Malawi and taking regular chloroquine prophylaxis. Resistance was confirmed by in vitro testing of his parasites for chloroquine and pyrimethamine. The possibility of Fansidar®-resistant falciparum malaria was also suggested in this case. American expatriates residing in or traveling to Malawi are advised to either take both chloroquine and Fansidar®, or alternatively amodiaquine or doxycycline alone. Any breakthrough of slide-proven falciparum malaria in these individuals should be seriously suspected to be chloroquine- and Fansidar®-resistant malaria, and should be treated with quinine and tetracycline.
| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 205 | 80 | 3 |
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| PDF Downloads | 3 | 2 | 0 |