Comparative Susceptibility of Mosquito Species and Strains to Oral and Parenteral Infection with Dengue and Japanese Encephalitis Viruses

Leon Rosen Arbovirus Program, Pacific Biomedical Research Center, University of Hawaii, School of Hygiene and Public Health, Johns Hopkins University, U.S. Naval Medical Research Unit No. 2, 3675 Kilauea Ave., Honolulu, Hawaii 96816, Taiwan

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Lloyd E. Roseboom Arbovirus Program, Pacific Biomedical Research Center, University of Hawaii, School of Hygiene and Public Health, Johns Hopkins University, U.S. Naval Medical Research Unit No. 2, 3675 Kilauea Ave., Honolulu, Hawaii 96816, Taiwan

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Duane J. Gubler Arbovirus Program, Pacific Biomedical Research Center, University of Hawaii, School of Hygiene and Public Health, Johns Hopkins University, U.S. Naval Medical Research Unit No. 2, 3675 Kilauea Ave., Honolulu, Hawaii 96816, Taiwan

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Jih Ching Lien Arbovirus Program, Pacific Biomedical Research Center, University of Hawaii, School of Hygiene and Public Health, Johns Hopkins University, U.S. Naval Medical Research Unit No. 2, 3675 Kilauea Ave., Honolulu, Hawaii 96816, Taiwan

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Byron N. Chaniotis Arbovirus Program, Pacific Biomedical Research Center, University of Hawaii, School of Hygiene and Public Health, Johns Hopkins University, U.S. Naval Medical Research Unit No. 2, 3675 Kilauea Ave., Honolulu, Hawaii 96816, Taiwan

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DOI:
https://doi.org/10.4269/ajtmh.1985.34.603
Volume/Issue:
Volume 34: Issue 3
Page(s):
603–615
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Thirty-four strains of Asian and Pacific mosquitoes belonging to 22 species of 7 genera were compared for oral and/or parenteral susceptibility to infection with 1 or more strains of each of the 4 dengue serotypes. Surprisingly, several species of common man-biting Aedes were much more susceptible to oral infection with each of the 4 dengue serotypes than was Aedes aegypti. These species included Aedes albopictus and members of the scutellaris group of the subgenus Stegomyia found on South Pacific islands. Mosquito strains and species relatively susceptible to 1 dengue serotype usually were relatively susceptible to the others also.

Almost all species of Aedes tested were uniformly susceptible to parenteral infection with the dengue viruses but, with the exception of a species of Tripteroides, species of all other genera were comparatively resistant to that mode of infection. Dengue viruses usually replicated to about the same extent in orally-infected mosquitoes as they did in parenterally-infected specimens of the same species.

Seventeen species of mosquitoes of 7 genera also were tested for parenteral susceptibility to infection with Japanese encephalitis virus. With the possible exception of 2 species of Anopheles, the virus replicated to about the same degree in all species tested and achieved levels considerably higher than did any of the dengue viruses in the same mosquito strain and species held under the same conditions.

Author Notes

Present address: Dengue Branch, San Juan Laboratories, Center for Infectious Diseases, GPO Box 4532, San Juan, Puerto Rico 00936.

Present address: Taiwan Provincial Institute of Infectious Diseases, Taipei, Taiwan.

Present address: USA MEDDAC-PANAMA, APO Miami, Florida 34004.

Copyright:
Copyright © 1985 by The American Society of Tropical Medicine and Hygiene 1985
Accepted:
30 Jul 1984
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Published Online:
May 1985
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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