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Serological Evidence of Hantaan Virus Infection in the United States
R. Yanagihara
R. Yanagihara
Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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C.-T. Chin
C.-T. Chin
Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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M. B. Weiss
M. B. Weiss
Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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D. C. Gajdusek
D. C. Gajdusek
Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland
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A. R. Diwan
A. R. Diwan
Department of Tropical Medicine and Medical Microbiology, University of Hawaii, School of Medicine, Honolulu, Hawaii
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J. B. Poland
J. B. Poland
Vector-Borne Viral Diseases Division, Centers for Disease Control, Fort Collins, Colorado
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K. T. Kleeman
K. T. Kleeman
State Laboratory of Public Health, Raleigh, North Carolina
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C. M. Wilfert
C. M. Wilfert
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina
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G. Meiklejohn
G. Meiklejohn
Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado
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W. P. Glezen
W. P. Glezen
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas
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We found low titers of fluorescent antibodies against Hantaan virus, the etiologic agent of Korean hemorrhagic fever, in sera from 7 of 1,035 patients with febrile illnesses of unknown origin and from 6 of 664 blood donors in the United States. All but 1 of these individuals possessed neutralizing antibodies against Hantaan virus. This was a 31-year-old research technician who had worked with laboratory rodents with virus-induced tumors, but had not traveled abroad, suggesting that infection with Hantaan virus or a closely related agent was locally acquired. However, the precise source of his infection remains unclear.
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| Past two years | Past Year | Past 30 Days | |
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