Successful Praziquantel Treatment of Paragonimiasis Following Bithionol Failure

A Case Report

Richard J. JohnsonDepartment of Medicine

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Steven B. DunningDepartment of Laboratory Medicine, University of Washington, Seattle, Washington 98195

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Barbara H. MinshewSea-Mar Community Health Clinic, Seattle, Washington

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Elaine C. JongDepartment of Medicine

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A patient from Southeast Asia with cough and hemoptysis was documented to have pulmonary paragonimiasis. Initial treatment with bithionol failed. The patient was then treated with praziquantel 75 mg/kg body weight a day for 2 days under an investigational protocol. Subsequent follow-up studies showed clinical improvement and indicated parasitologic cure. A concurrent asymptomatic Clonorchis infection was also cured following praziquantel treatment. Side effects were minor.

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