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Mefloquine, a new antimalarial which has been effective in curing malaria due to Plasmodium falciparum and P. vivax, was used for the first time in a patient infected with P. malariae. Treatment was successful, and the relatively long parasite clearance time and fever clearance time were probably characteristic of P. malariae rather than true drug resistance.
Address reprint requests to: Kenneth E. Dixon, LTC, MC, Department of Preventive Medicine/Biometrics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland 20814.