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Growth and Transovarial Transmission of Chandipura Virus (Rhabdoviridae: Vesiculovirus) in Phlebotomus Papatasi
Robert B. Tesh
Robert B. Tesh
Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, P. O. Box 333, New Haven, Connecticut 06510
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Govind B. Modi
Govind B. Modi
Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, P. O. Box 333, New Haven, Connecticut 06510
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Chandipura virus multipled in sand flies (Phlebotomus papatasi) following intrathoracic inoculation. Within 24 hours, mean virus titers in infected flies increased approximately 4 logs. Experimentally infected P. papatasi transmitted the virus by bite to newborn mice and by transovarial transmission to their progeny. Eight percent of the F1 offspring of experimentally infected female parents were infected with Chandipura virus.
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