Comparison of the Enzyme-Linked Immunosorbent Assay (Elisa) with Standard Tests used to Detect Yellow Fever Virus Antibodies

V. Deubel Department of Virology, Institut Pasteur, Dakar, Senegal

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V. Mouly Department of Virology, Institut Pasteur, Dakar, Senegal

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J. J. Salaun Department of Virology, Institut Pasteur, Dakar, Senegal

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C. Adam Department of Virology, Institut Pasteur, Dakar, Senegal

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M. M. Diop Department of Virology, Institut Pasteur, Dakar, Senegal

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J. P. Digoutte Department of Virology, Institut Pasteur, Dakar, Senegal

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DOI:
https://doi.org/10.4269/ajtmh.1983.32.565
Volume/Issue:
Volume 32: Issue 3
Page(s):
565–568
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The enzyme-linked immunosorbent assay (ELISA) was used to detect antibodies to yellow fever virus in 110 sera from patients living in an epidemic yellow fever area. The results were then compared with those obtained with the hemagglutination-inhibition (HI), complement-fixation (CF), neutralization (NT), and indirect immunofluorescence (IFA) tests. This ELISA, which used a type-specific antigen, showed the same results as the NT test and was found to be more sensitive and more specific than the HI and CF tests.

Author Notes

Copyright:
Copyright © 1983 by The American Society of Tropical Medicine and Hygiene 1983
Accepted:
30 Sep 1982
|
Published Online:
May 1983
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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