A Simple Field Kit for the Determination of Drug Susceptibility in Plasmodium Falciparum

Phuc Nguyen-Dinh Malaria Branch, Parasitic Diseases Division, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Section de Recherches, Service National des Endemies Majeures, Ministère de la Santé, Atlanta, Georgia 30333, Republic of Haiti

Search for other papers by Phuc Nguyen-Dinh in
Current site
Google Scholar
PubMed Close
,
Roc Magloire Malaria Branch, Parasitic Diseases Division, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Section de Recherches, Service National des Endemies Majeures, Ministère de la Santé, Atlanta, Georgia 30333, Republic of Haiti

Search for other papers by Roc Magloire in
Current site
Google Scholar
PubMed Close
, and
William Chin Malaria Branch, Parasitic Diseases Division, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human Services, Section de Recherches, Service National des Endemies Majeures, Ministère de la Santé, Atlanta, Georgia 30333, Republic of Haiti

Search for other papers by William Chin in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.4269/ajtmh.1983.32.452
Volume/Issue:
Volume 32: Issue 3
Page(s):
452–455
Restricted access
Get Permissions

A field kit has been developed which greatly simplifies the performance of the 48-hour in vitro test for drug resistance in Plasmodium falciparum. The kit uses an easily reconstituted lyophilized culture medium, and requires only a fingerprick blood sample. In parallel tests with 13 isolates of P. falciparum in Haiti, the new technique had a success rate equal to that of the previously described method, with comparable results in terms of parasite susceptibility in vitro to chloroquine and pyrimethamine.

Author Notes

Copyright:
Copyright © 1983 by The American Society of Tropical Medicine and Hygiene 1983
Accepted:
16 Aug 1982
|
Published Online:
May 1983
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
Past two years Past Year Past 30 Days
Abstract Views 1016 627 52
Full Text Views 7 1 0
PDF Downloads 4 1 0
 

 

 

 
 
Affiliate Membership Banner
 
 
Research for Health Information Banner
 
 
CLOCKSS
 
 
 
Society Publishers Coalition Banner
Save