Effect of Praziquantel on Antigenemia in Murine Schistosomiasis

Joel K. WeltmanDivision of Biomedical Sciences, Brown University, Providence, Rhode Island 02912

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Abstract. A substantial portion (63%) of circulating schistosomal antigen was cleared from the serum of hyperinfected mice within 72 hours after treatment with the helminthocide, praziquantel. This result suggests that circulating antigen may be a diagnostically useful marker for active schistosomiasis.