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An Onchocercal Nodule Appearing during Diethylcarbamazine Therapy
Eric S. Boye
Eric S. Boye
Department of Infectious and Parasitic Disease Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306
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Daniel H. Connor
Daniel H. Connor
Department of Infectious and Parasitic Disease Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306
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Abstract. We describe the appearance of an onchocercal nodule in a patient during treatment with diethylcarbamazine (DEC). This is a unique occurrence. DEC has been employed in the treatment of onchocerciasis for many years, but there have been no reports of any effects of DEC on nodules. Histopathological studies in which nodules have been examined before and after treatment of patients with DEC have not revealed any changes induced by such treatment. The histological appearance of this nodule is described, and the probable mechanism of its enlargement is discussed.
Author Notes
Research Fellow, World Health Organization, currently assigned to WHO Reference Laboratory for Filarial Infections of Man, at the Department of Infectious and Parasitic Disease Pathology, Armed Forces Institute of Pathology.
| Past two years | Past Year | Past 30 Days | |
|---|---|---|---|
| Abstract Views | 934 | 687 | 19 |
| Full Text Views | 9 | 2 | 2 |
| PDF Downloads | 8 | 3 | 3 |