Serological Evidence of Human Infection with Congo-Crimean Hemorrhagic Fever Virus in Greece

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  • Department of Microbiology, School of Medicine, Aristotelian University of Thessaloniki, Yale Arbovirus Research Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, Thessaloniki, Greece
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Sixty-five residents in a rural area of northern Greece were tested for circulating antibodies against Congo-Crimean hemorrhagic fever virus; antibodies were demonstrated in four by immunofluorescence and hemagglutination-inhibition tests. While the virus had been previously isolated in the area, this is the first time that evidence of human infection in nature has been observed in Greece.