Prepared under the auspices of The American Society of Clinical Pathologists. By John A. Kolmer, M.D., Dr.P.H., D.Sc., LL.D., and Fred Boerner, V.M.D. Assisted by C. Z. Garber, A.B., M.D., and Committees of The American Society of Clinical Pathologists. Pp. I–XXII. 1–663. D. Appleton and Company, New York and London, 1931
Since submission and publication of the recent article by B. A. Nagy, S. K. File, and J. H. Smith, “Changes in enteric vasculature of mice infected with Schistosoma mansoni” (Am. J. Trop. Med. Hyg., 30: 999–1009), two additional studies bearing on our results have come to my attention. The first article appeared after submission of our paper and deals in vivo with much younger infections than those we studied; however, Dr. Bloch presents evidence of sacculations of intestinal venules adjacent to eggs from which he infers that the eggs elaborate a vasoactive substance. This effect is apparently quite localized since sacculation rather than dilatation of the vessel was observed. However, it is difficult to postulate that such a substance would produce venular muscular relaxation (sacculation) at the same time it produces hepatic portal vein sphincter contraction which could explain some of our findings. Nonetheless, these sacculations may be what we observed as micro-aneurysms in our preparations.