Thrombocytopenia in Leptospirosis

Charles N. Edwards Department of Medicine, Queen Elizabeth Hospital and University of the West Indies, Medical Research Council/Barbados Government Leptospirosis Project, Barbados

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George D. Nicholson Department of Medicine, Queen Elizabeth Hospital and University of the West Indies, Medical Research Council/Barbados Government Leptospirosis Project, Barbados

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Christopher O. R. Everard Department of Medicine, Queen Elizabeth Hospital and University of the West Indies, Medical Research Council/Barbados Government Leptospirosis Project, Barbados

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DOI:
https://doi.org/10.4269/ajtmh.1982.31.827
Volume/Issue:
Volume 31: Issue 4
Page(s):
827–829
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In a retrospective study undertaken to document the frequency of thrombocytopenia in cases of leptospirosis, 18 of 32 patients (56.3%) had a platelet count of 100 × 103/mm3 or less. Renal failure occurred in 72.2% of thrombocytopenic patients and in 21.4% of patients with normal platelet counts. The association of thrombocytopenia and renal failure was significant (P < 0.02). The common occurrence of thrombocytopenia and its association with acute renal failure in patients with leptospirosis has not previously been reported.

Author Notes

Accepted:
15 Jan 1982
|
Published Online:
Jul 1982
Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
Print ISSN:
0002-9637
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