Recovery of a Lassa-Related Arenavirus in Zimbabwe

View More View Less
  • Special Pathogens Branch, Virology Division, Center for Infectious Diseases, Centers for Disease Control, U.S. Department of Health and Human Services, Public Health Service, Blair Research Laboratory, Department of Virology, University of Ibadan, Atlanta, Georgia 30333, Zimbabwe

Immunofluorescent antibodies to “Mozambique” virus, a close relative of Lassa virus, were found in 11 of 55 Mastomys natalensis and 1 of 13 Aethomys chrysophilus rodents captured near Que Que and Chiredzi, Zimbabwe. Six strains of Mozambique virus, identified by use of specific monoclonal antibodies to the agent, were recovered from visceral tissues of M. natalensis rodents. All Mastomys having virus or antibodies to this agent were of the chromosomal form 2N = 32 (M. natalensis). These data extend the area of geographic occurrence of this virus, which was initially recognized in Mozambique and which may represent a naturally attenuated antigenic variant of human pathogenic West African Lassa virus.

Author Notes

Recipient of Fogarty International Fellowship at Virology Division, Center for Infectious Diseases, Centers for Disease Control.

Save