Intermittent Excretion of Rabies Virus in the Saliva of a Dog Two and Six Months after it Had Recovered from Experimental Rabies

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  • Viral Zoonoses Branch, Virology Division, Center for Infectious Diseases, Centers for Disease Control (Lawrenceville Facility), Public Health Service, U.S. Department of Health and Human Services, P.O. Box 363, Lawrenceville, Georgia 30246

A dog inoculated with a rabies virus isolate from the saliva of an apparently healthy Ethiopian dog was followed for more than 9 months. Saliva and blood specimens were collected three times weekly and cerebrospinal fluid weekly. Saliva samples collected on days 42 and 169 after the dog's recovery produced fatal rabies infections in mice inoculated intracerebrally.

Author Notes

Visiting Scientist. This work was done while the senior author was being supported by the Swedish Aid for Research Cooperation with Developing Countries Project 77/89A9-49 U-forsk, through the Department of Bacteriology and Epizootology, Biomedicum, P.O. Box 583, S-75123, Uppsala, Sweden.