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In 14 villages located in the West African savanna belt, 1,305 people were examined for microfilariae in blood and skin. The results indicate that the associations between filariae in infected patients are not the result of chance alone. The frequency of associations between Wuchereria bancrofti and Tetrapetalonema perstans was highly significant, whereas Onchocerca volvulus appeared to be associated with W. bancrofti only in the absence of D. perstans.