The Suppressive Treatment of Malaria in a Rural Village with Primaquine and Plaquenil

Herbert C. ClarkGorgas Memorial Laboratory

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Summary and Conclusions

Ninety-three dark-skinned individuals (42 adults and 51 children) living in a highly malarious village in Panama, were given suppressive treatments weekly with a combination of primaquine and Plaquenil for from 20 to 26 weeks. After the first 3 weeks, only 6 were found positive for malaria parasites on weekly examination of thick blood-films, although the percentage of positives was 52.2% at the start. No toxic results were noted either in children or adults.