Clonorchiasis: A Report of Four Cases and Discussion of Unusual Manifestations

Tsieh SunDepartment of Pathology, Cornell University Medical College, Department of Laboratories, North Shore University Hospital, New York, New York 10021

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Clonorchiasis is still a problem for Asian immigrants to North America, and is occasionally seen among American residents who contract the disease during long-term or short-term visits to endemic areas. The incidence of clonorchiasis is especially high among Chinese immigrants from Hong Kong. The acute symptoms most frequently encountered in this group of patients are those of recurrent pyogenic cholangitis and acute pancreatitis. Two American cases are reported together with a brief discussion of the pathology and immunology of this disease. Two unusual lesions in Hong Kong patients, an egg-granuloma of the liver and an adenoma of the bile duct, are also discussed.