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Transplacental Transmission of Venezuelan Equine Encephalitis Virus in Horses

Gustavo JustinesGorgas Memorial Laboratory, Panama, and Ministerio de Desarrollo Agropecuario, Panama, Republic of Panama

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Hirisnel SucreGorgas Memorial Laboratory, Panama, and Ministerio de Desarrollo Agropecuario, Panama, Republic of Panama

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Otto AlvarezGorgas Memorial Laboratory, Panama, and Ministerio de Desarrollo Agropecuario, Panama, Republic of Panama

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Transplacental passage of Venezuelan equine encephalitis virus, epizootic strain P-676, occurred in four of nine fetuses studied. The mares were infected near term. Virus was recovered in high titer from fetal blood and organs, while no virus was detected in maternal blood but neutralizing antibodies were present. No evidence of in utero infection was found in two fetuses from mares infected with MF-8, another epizootic strain of Venezuelan equine encephalitis virus.

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