Serologic Cross-Reactions with Sera from Patients with Echinococcosis and Cysticercosis

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  • Parasitic Diseases Division, Bureau of Epidemiology, and Parasitology Division, Bureau of Laboratories, Center for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333

Serum specimens from persons with pathologically confirmed Echinococcus granulosus hydatidosis and Taenia solium cysticercosis were tested in indirect hemagglutination tests using both Echinococcus and Taenia antigens. There were cross-reactions with most sera, and it was not possible to distinguish specific reactions by comparing titers with the homologous or heterologous antigens. Using immunoelectrophoresis or double diffusion tests with E. granulosus antigens, the Echinococcus-specific arc 5 was demonstrated in 11 of 21 hydatidosis sera and in 1 of 20 cysticercosis sera.