The Major Serological Antigen (MSA1) from Schistosoma mansoni Eggs is a “Circumoval” Precipitinogen

George V. Hillyer Laboratory of Parasite Immunology, Department of Biology, University of Puerto Rico, Department of Pathology, The University of Chicago, Pritzker School of Medicine, Rio Piedras, Puerto Rico 00931

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Ronald P. Pelley Laboratory of Parasite Immunology, Department of Biology, University of Puerto Rico, Department of Pathology, The University of Chicago, Pritzker School of Medicine, Rio Piedras, Puerto Rico 00931

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A monoclonal hybridoma antibody to the major serological egg antigen of Schistosoma mansoni (anti-MSA1) reacted with schistosome eggs, forming a circumoval precipitate. This precipitate was seen when anti-MSA1 was incubated with S. mansoni, S. haematobium, and S. japonicum eggs.

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