Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
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0002-9637
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Applicability of Different Antigen Preparations in the Enzyme-Linked Immunosorbent Assay for Schistosomiasis mansoni

A. M. DeelderUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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D. KornelisUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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M. MakbinUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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H. N. NoordpoolUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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R. M. CodfriedUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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J. P. RotmansUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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B. F. J. OostburgUniversity of Leiden, Medical Center, Department of Parasitology, Medical Scientific Institute, Department of Parasitology, Leiden, Netherlands

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DOI:
https://doi.org/10.4269/ajtmh.1980.29.401
Volume/Issue:
Volume 29: Issue 3
Page(s):
401–410
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The applicability of seven different antigen preparations for the detection of antibodies against Schistosoma mansoni was tested in the enzyme-linked immunosorbent assay. For this purpose, sera from children and adults from Surinam infected with S. mansoni were screened for the presence of specific antibodies against the various antigens. With all antigens, generally better results were obtained with the sera from children than with those from adults. The best results were obtained when the trichloroacetic acid-soluble fraction of adult worm antigen (containing the proteoglycan circulating anodic antigen) was used.
Copyright:
Copyright © 1980 by The American Society of Tropical Medicine and Hygiene 1980
Accepted:
15 Sep 1979
|
Published Online:
May 1980
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