Schistosomiasis Haematobia in Coast Province Kenya

Relationship between Egg Output and Morbidity

K. S. Warren Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Radiology, Kenyatta General Hospital and Division of Vector Borne Diseases, Ministry of Health, Cleveland, Ohio 44106, Kenya

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A. A. F. Mahmoud Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Radiology, Kenyatta General Hospital and Division of Vector Borne Diseases, Ministry of Health, Cleveland, Ohio 44106, Kenya

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J. F. Muruka Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Radiology, Kenyatta General Hospital and Division of Vector Borne Diseases, Ministry of Health, Cleveland, Ohio 44106, Kenya

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L. R. Whittaker Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Radiology, Kenyatta General Hospital and Division of Vector Borne Diseases, Ministry of Health, Cleveland, Ohio 44106, Kenya

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J. H. Ouma Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Radiology, Kenyatta General Hospital and Division of Vector Borne Diseases, Ministry of Health, Cleveland, Ohio 44106, Kenya

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T. K. Arap Siongok Division of Geographic Medicine, Department of Medicine, Case Western Reserve University and University Hospitals, Department of Radiology, Kenyatta General Hospital and Division of Vector Borne Diseases, Ministry of Health, Cleveland, Ohio 44106, Kenya

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Several studies of schistosomiasis haematobia in Africa have revealed a correlation between intensity of infection as measured by urine egg counts and severity of disease as determined by intravenous pyelography. The present study consisted of a survey of 390 school children in the coastal area of Kenya involving a single egg count, and intravenous pyelograms in a stratified random sample of 69 children; the results showed a greater prevalence of urinary tract disease in those with higher intensities of infection. This survey was then followed by a more detailed study in which nine consecutive daily egg counts were done on 121 children; 17 of these children, subdivided into three groups with different intensities of infection, were given intravenous pyelograms. The results were similar in the 11 children with minimal and moderate counts (averaging, respectively, <1 egg and 167 eggs/10 ml urine daily), with approximately 30% having bladder or renal abnormalities. In comparison, all of the six children with heavy counts (averaging 1,288 eggs/10 ml urine daily) had bladder lesions and five of them had renal lesions.

Author Notes

Present address: The Rockefeller Foundation, New York City, New York 10036.

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