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Damage to Trichinella Spiralis Newborn Larvae by Eosinophil Major Basic Protein
Donald L. Wassom
Donald L. Wassom
Allergic Diseases Research Laboratory, Departments of Medicine and Immunology, Mayo Clinic and Foundation, Rochester, Minnesota 55901
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Gerald J. Gleich
Gerald J. Gleich
Allergic Diseases Research Laboratory, Departments of Medicine and Immunology, Mayo Clinic and Foundation, Rochester, Minnesota 55901
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Purified eosinophil major basic protein damaged newborn larvae of Trichinella spiralis when added to in vitro cultures. Damaged larvae were stiffened, immobile, and showed a granular appearance by light microscopy. Larvae in control cultures and in cultures containing equimolar concentrations of other basic proteins failed to exhibit such damage.
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