Cover The American Journal of Tropical Medicine and Hygiene
The American Journal of Tropical Medicine and Hygiene
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0002-9637
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Relationships of Bunyamwera Group Viruses by Neutralization

Ann R. HuntArbovirus Reference Branch, Vector-Borne Diseases Division, Bureau of Laboratories, Center for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Fort Collins, Colorado 80522

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Charles H. CalisherArbovirus Reference Branch, Vector-Borne Diseases Division, Bureau of Laboratories, Center for Disease Control, Public Health Service, U.S. Department of Health, Education, and Welfare, Fort Collins, Colorado 80522

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DOI:
https://doi.org/10.4269/ajtmh.1979.28.740
Volume/Issue:
Volume 28: Issue 4
Page(s):
740–749
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A standardized serum dilution plaque reduction neutralization test was used for cross-neutralization studies of 23 strains of Bunyamwera serogroup viruses. Antigenic relationships were determined by inspection of the neutralization tests results as well as by numerical taxonomic analysis. Based on these analyses five complexes, containing 1–11 viruses, were distinguished. Little or no cross-reactivity was observed between viruses of different complexes. Three of the viruses tested were indistinguishable from prototypes and probably represent strains or varieties of those prototypes. A tentative classification scheme for the Bunyamwera group is presented.

Author Notes

Present address: Biology Department, West Virginia University, Morgantown, West Virginia 26506.

Copyright:
Copyright © 1979 by The American Society of Tropical Medicine and Hygiene 1979
Accepted:
23 Dec 1978
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Published Online:
Jul 1979
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