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Cutaneous Leishmaniasis—a Case with Persistent Organisms after Treatment in Presence of Normal Immune Response
Franklin A. Neva
Franklin A. Neva
Laboratory of Parasitic Diseases and Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20205
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David Wyler
David Wyler
Laboratory of Parasitic Diseases and Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20205
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Theodore Nash
Theodore Nash
Laboratory of Parasitic Diseases and Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20205
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A Peace Corps volunteer in Senegal, West Africa contracted cutaneous leishmaniasis which had several noteworthy features. One of the three presenting cutaneous ulcers was associated with subcutaneous nodules and viable organisms were recovered from healing lesions after multiple courses of treatment, including amphotericin B. Yet, the patient was found to exhibit both humoral and cell mediated features of normal immunologic responsiveness. Ultimately, clinical and parasitological cure occurred. The patient's organism was found to produce lesions in the foot pads of mice.
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| Past two years | Past Year | Past 30 Days | |
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| Abstract Views | 714 | 413 | 113 |
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| PDF Downloads | 9 | 2 | 0 |