Diarrhea Associated with Rotavirus in Rural Guatemala: A Longitudinal Study of 24 Infants and Young Children

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  • Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Instituto de Nutrición de Centro America y Panamá, Instituto de Investigaciones en Salúd, Universidad de Costa Rica, Bethesda, Maryland 20014, Guatemala

A population of 24 infants and young children followed prospectively during the first 3 years of life was studied for the occurrence of rotavirus infection by using enzyme-linked immunosorbent assay to detect virus in stools. Infection with rotavirus was associated with 26 (14.2%) of 183 selected diarrheal episodes. Twenty of the 24 infants and young children had diarrhea associated with rotavirus on at least one occasion and six had two such episodes. Rotavirus infection was documented in over 50% of the dehydrating episodes studied, thus further indicating the importance of rotavirus in this population.